El síndrome de Smith-Lemli-Opitz (SLOS) es un síndrome congénito de anomalía múltiple y deterioro cognitivo, causado por una deficiencia en la enzima 7-DHC reductasa. El grado de cumplimiento de un indicador congénito se expresa mediante una relación directa del desempeño de neutralidad representando un dominio de valores neutrosóficos para modelar la incertidumbre. La presente investigación describe una solución a la problemática planteada mediante el desarrollo de un método para la evaluación del Síndrome de Smith-Lemli-Opitz. El SLOS, causado por mutaciones en (...) el gen DHCR7, presenta variabilidad fenotípica, malformaciones múltiples y discapacidad intelectual. No tiene cura, y la suplementación con colesterol es de eficacia limitada. La revisión destaca la necesidad de diagnóstico prenatal preciso y nuevas intervenciones terapéuticas, como estatinas y antioxidantes, para mejorar la calidad de vida de los pacientes. (shrink)

Narrowly understood, veganism is the practice of excluding all animal products from one’s diet, with the exception of human milk. More broadly, veganism is not only a food ethics, but it encompasses all other areas of life. As defined by the Vegan Society when it became an established charity in the UK in 1979, veganism is best understood as “a philosophy and way of living which seeks to exclude – as far as is possible and practicable – all forms of (...) exploitation of, and cruelty to, animals for food, clothing or any other purpose; and by extension, promotes the development and use of animal-free alternatives for the benefit of humans, animals and the environment”. There are two main moral justifications for veganism, both of which rely on a common assumption: that sentience, i.e., the capacity to feel pleasure and pain, is the necessary and sufficient trait to be morally considerable. In what follows, I present these two justifications and a third one which, although less popular, captures some core intuitions among vegans. I then present a challenge faced by veganism and two arguments that reject it as discriminatory, and briefly conclude. (shrink)

Given the conceptual gap in the global justice debate today (where most of the talk is about the duties of the rich, but little is said about what the poor may do for themselves), in this article I reintroduce the idea of a right of necessity. I first delineate a normative framework for such a right, inspired by these historical accounts. I then offer a contemporary case where the exercise of the right of necessity would be morally legitimate according to (...) that framework – even though illegal and probably condemned by the standard moral norms. The case is that of a small group of Paraguayan campesinos (small farmers) suffering from the effects of a severe drought. In the third part, I introduce the concept of noncivil disobedience: I call an act of noncivil disobedience a conscientious, public, illegal and forcible act whose performance, while not necessarily intended directly as a means to bring about social and/or political change, may help to trigger these changes indirectly. In the fourth part, I suggest that certain instances where the right of necessity is overtly exercised – as in the case of the famine-struck Paraguayan campesinos – may also be interpreted in terms of noncivil disobedience, insofar as they serve a double function: as a means of satisfying immediate need, and as a marker of discontent in a society where the equal rights of individuals are a nominal ideal which remains unfulfilled in practice. I then address two objections that may be raised against resurrecting the idea of a right of necessity and identifying it in certain instances with noncivil disobedience. I conclude by suggesting that, at the point of convergence between the two, a basic right like the right of necessity recovers its value as an active, (rather than passive) entitlement of its holders, while the use of force enters the picture as a legitimate means that – at least under certain circumstances – may be resorted to within the limits of civil society. (shrink)

At the basis of modern natural law theories, the concept of the suum, or what belongs to the person (in Latin, his, her, its, their own), has received little scholarly attention despite its importance both in explaining and justifying not only the genealogy of property, but also that of morality and war.1 In this paper I examine Hugo Grotius's what it is, what things it includes, what rights it gives rise to and how it is extended in the transition from (...) the state of nature to civil society. I then briefly point out how bringing this concept back to the fore could help to illuminate the current discussion on the foundations of basic human rights, and to evaluate cases where these seem to clash with property rights. (shrink)

From the end of the twelfth century until the middle of the eighteenth century, the concept of a right of necessity –i.e. the moral prerogative of an agent, given certain conditions, to use or take someone else’s property in order to get out of his plight– was common among moral and political philosophers, who took it to be a valid exception to the standard moral and legal rules. In this essay, I analyze Samuel Pufendorf’s account of such a right, founded (...) on the basic instinct of self-preservation and on the notion that, in civil society, we have certain minimal duties of humanity towards each other. I review Pufendorf’s secularized account of natural law, his conception of the civil state, and the function of private property. I then turn to his criticism of Grotius’s understanding of the right of necessity as a retreat to the pre-civil right of common use, and defend his account against some recent criticisms. Finally, I examine the conditions deemed necessary and jointly sufficient for this right to be claimable, and conclude by pointing to the main strengths of this account. Keywords: Samuel Pufendorf, Hugo Grotius, right of necessity, duty of humanity, private property. (shrink)

By giving sympathy a central role, Adam Smith’s Theory of Moral Sentiments (1759) can be regarded as one of the ‘enlightened’ moral theories of the Enlightenment, insofar as it widened the scope of moral consideration beyond the traditionally restricted boundary of human beings. This, although the author himself does not seem to have been aware of this fact. In this paper, I want to focus on two aspects which I think lead to this conclusion. First, by making sentience the requisite (...) to be taken into moral consideration, nonhuman animals in Smith’s moral theory can count as moral patients towards whom we should exercise the virtue of beneficence (if not justice). Secondly, Smith’s idea of morality as working in concentric circles –generating more stringent duties towards those closer to us– could explain and perhaps also justify our caring for some nonhuman animals, especially pets. (shrink)

Perception of time is susceptible to distortions; among other factors, it has been suggested that the perceived duration of a stimulus is affected by the observer’s expectations. It has been hypothesized that the duration of an oddball stimulus is overestimated because it is unexpected, whereas repeated stimuli have a shorter perceived duration because they are expected. However, recent findings suggest instead that fulfilled expectations about a stimulus elicit an increase in perceived duration, and that the oddball effect occurs because the (...) oddball is a target stimulus, not because it is unexpected. Therefore, it has been suggested that top-down attention is sometimes sufficient to explain this effect, and sometimes only necessary, with an additional contribution from saliency. However, how the expectedness of a target stimulus and its salient features affect its perceived duration is still an open question. In the present study, participants’ expectations about and the saliency of target stimuli were orthogonally manipulated with stimuli presented on a short (Experiment 1) or long (Experiment 2) temporal scale. Four repetitive standard stimuli preceded each target stimulus in a task in which participants judged whether the target was longer or shorter in duration than the standards. Engagement of top-down attention to target stimuli increased their perceived duration to the same extent irrespective of their expectedness. A small but significant additional contribution to this effect from the saliency of target stimuli was dependent on the temporal scale of stimulus presentation. In Experiment 1, saliency only significantly increased perceived duration in the case of expected target stimuli. In contrast, in Experiment 2, saliency exerted a significant effect on the overestimation elicited by unexpected target stimuli, but the contribution of this variable was eliminated in the case of expected target stimuli. These findings point to top-down attention as the primary cognitive mechanism underlying the perceptual extraction and processing of task-relevant information, which may be strongly correlated with perceived duration. Furthermore, the scalar properties of timing were observed, favoring the pacemaker-accumulator model of timing as the underlying timing mechanism. (shrink)

Una idea casi universalmente aceptada es que es que la filosofía y la ciencia por naturaleza buscan la verdad. No obstante, para que alcancen la Verdad requieren a fortiori de la fe. A partir de estas ideas, nuestra reflexión está organizada en tres apartados: en el primero abordamos la necesidad de la metafísica como disciplina que encuentra los principios en la naturaleza. Así como, la ciencia gracias a la metafísica encuentra las leyes de esta, pero sólo con ayuda de la (...) fe; en la segunda idea nos centramos en explicar el método de la ciencia y nos preguntamos sí sus formas y metodologías van de acuerdo con la fe. La última idea, trata la dimensión de las ciencias sociales cara al Desarrollo Humano (DH). El argumento que se desarrolla en este apartado sostiene que, el motivo por el cual el hombre, con su razón, busca la verdad; es para dar sentido a su existencia. No obstante, hay que reflexionar sobre el devenir de las Ciencias Sociales puesto que ante el establecimiento de linderos, la inflexión de métodos y metodologías se ha desdibujado e incomprendido de los hechos presentes en la realidad y no se ha tendido a la búsqueda de la verdad. Finalmente, se presentan nuestras conclusiones que ahondan en la propuesta del DH y la bibliografía utilizada para elaborar este trabajo. (shrink)

In ‘Excusing Mistakes of Law’, Gideon Yaffe sets out to ‘vindicate’ the claim ‘that mistakes of law never excuse’ by ‘identifying the truth that is groped for but not grasped by those who assert that ignorance of law is no excuse’. Yaffe does not offer a defence of the claim that mistakes of law never excuse. That claim, Yaffe argues, is false. Yaffe’s article is, rather, an effort to assess what plausible thought might be behind the idea that mistakes of (...) law often should not excuse. (Yaffe is interested in more than just the descriptive claim that in Anglo-American legal jurisdictions mistakes of law routinely do not, in fact, excuse.) More particularly, Yaffe is interested in what plausible normative justification there might be for this asymmetric pattern: -/- Asymmetry: False beliefs about non-legal facts often excuse, but false beliefs about the law rarely excuse. -/- Yaffe offers a complex argument in support of Asymmetry. This paper is organised around my reconstruction of Yaffe’s argument. I argue that Yaffe’s argument does not succeed, but that his argument provides a template for an argument that could succeed. (shrink)

Para comprender la visión peirceana acerca de la subjetividad semiótica es necesario establecer antes tres referentes. Cada uno de estos referentes tiene un constructo teórico efectuado por otra serie de nociones, que en este momento no me detendré a explicar, sin embargo, será necesario más adelante acudir a varias de estas nociones para intentar exponer mi tema de investigación. La filosofía peirceana es un sistema amplio y complejo, va madurando en el tiempo. Peirce va definiendo y redefiniendo sus conceptos, hasta (...) cierto punto lo realiza de una manera imbricada, este es su método. Se presenta la dificultad de que la construcción teórica peirceana depende de conceptos que se explican entre sí, lo que hace la labor de investigación y exposición difícil, pues para fin de exponer una idea se requiere acceder a diferentes referentes conceptuales simultáneamente hasta llegar a una noción central. (shrink)

he territorial impacts of climate change will affect millions. This will happen not only as a direct consequence of climate change, but also because of policies for mitigating it—for example, through the installation of large wind and solar farms, the conservation of land in its role as carbon sink, and the extraction of materials needed for renewable energy technologies. In this article, we offer an overview of the justice-related issues that these impacts create. The literature on climate justice and territory (...) is vast and spans a range of disciplines, so we limit our discussion to a specific understanding of territory and a specific understanding of injustice that arises from its loss. We understand territory as a normative concept that describes a place under some agent's jurisdiction, where the agent is a politically organized collective and where the jurisdictional rights over that place secure a relevant degree of self-determination for that collective. Accordingly, we consider that the main injustice connected to the loss of territory due to climate change is the loss or undermining of the ability to exercise the collective right to self-determination, which requires some control over the place. This can happen if a territorial agent literally loses the ground where to stand as a direct effect of climate change, raising issues of justice in relocation; or if their place changes due to mitigation policies, affecting their use and understanding of territory, raising issues of justice in energy transition. In concluding, we point to topics for future research. (shrink)

The concept of psychological trauma is polysemous and remains a subject of ongoing debate among scholars and researchers. One of the most significant discussions surrounding the definition of trauma is the relationship between traumatic events (TE), traumatic memory (TM) and trauma response (TR). Several definitions of trauma provided by world-renowned organizations present the TE as the primary element, suggesting a necessary causal relationship in which the TE is antecedent, and the TM and TR are consequent. I call this the _strong (...) causal view_. In this article, I argue that the strong causal view is problematic as it does not sufficiently account for important trauma-related effects that pose anomalies for the causal position. I argue in favor of two claims. First, in defining psychological trauma, we must move beyond the need for a strong TE-dependent causal relationship and instead adopt a _weak causal view_. To support this, I review the discussion of causation in philosophy of memory that pits causal theories against postcausal theories, and propose two principles that can aid this transition. Second, I propose that among the three elements, TR should be the most critical in defining trauma. My aim is to support those definitions of psychological trauma that focus on TR, as I believe they offer greater explanatory power —especially regarding anomalies that challenge the strong causal view— and are more centered on the survivors' experience than those focused on TE. (shrink)

The aim of this paper lies in characterizing the explanations and models used in the field of evolutionary developmental biology throughout its history. While manipulative experiments in controlled conditions have been useful to set the bases of the discipline and are still routinely performed, this approach supposes a tension between the reliability and the representativity of the conclusions. Given the recent changes in the understanding of evolutionary phenomena, different authors currently emphasize the need of avoiding excessive simplifications in experimental approaches, (...) incorporating the complexity of the analyzed systems as a relevant trait in the study of biological diversity. On the other hand, the fragile and contingent nature of evolutionary processes and the impossibility of intervening some of these phenomena underscore the importance of non-manipulative models that allow the elucidation of how-possibly mechanisms. We argue that a pluralism characterized by the integration of different kinds of explanations, models and metaphors used in evo-devo allows to exploit their respective advantages, favours interdisciplinarity and can contribute to form a representative description of evolutionary processes without relinquishing the local and detailed study of actual mechanisms. (shrink)

En este trabajo nos enfocamos fundamentalmente en responder dos interrogantes: (a) ¿Pueden las mujeres ser sujetos ilustrados desde la perspectiva de Hume? y en caso de responder afirmativamente, (b) ¿resulta esta ilustración emancipatoria en términos feministas? En primer lugar, reconstruimos las principales líneas de interpretación feministas de la obra de Hume para ubicar nuestra propuesta dentro de una corriente interpretativa poco explorada aún. En segundo lugar, precisamos el sentido que puede adoptar la noción de “ilustración” en la filosofía de Hume, (...) en discusión con debates de la literatura secundaria contemporánea. En tercer lugar, orientamos nuestra reflexión a responder el primero de los interrogantes e indagamos si las mujeres están incluidas dentro de los rasgos ilustrados que podemos reconocer en el pensamiento de Hume y en qué condiciones. En cuarto y último lugar, ensayamos una respuesta al segundo interrogante: si aquello que podemos interpretar como ilustración femenina en clave humeana constituye una vía para la emancipación de la dominación patriarcal o si, por el contrario, refuerza el sometimiento de las mujeres. (shrink)

According to the brain drain argument, there are good reasons for states to limit the exit of their skilled workers (more specifically, healthcare workers), because of the negative impacts this type of migration has for other members of the community from which they migrate. Some theorists criticise this argument as illiberal, while others support it and ground a duty to stay of the skilled workers on rather vague concepts like patriotic virtue, or the legitimate expectations of their state and co-citizens. (...) In this article, on the contrary, we suggest that the liberal conception of states’ legitimate political authority demands, and not just permits, that developing states from which migration of skilled workers occurs set up contractual mechanisms. These mechanisms will ensure that state-funded training in the health sector is provided against a commitment on the part of future professionals to reciprocate with their services for the benefits obtained. If one of the conditions for the state to maintain legitimate political authority is to provide basic services such as healthcare to its subjects (while respecting at the same time their autonomy and freedom), then this is what developing states affected by the brain drain ought to do. What we call the authority-based approach to the brain drain also helps to clarify the obligations that other states have not to interfere with these contractual mechanisms when they exist, and not to profit from their absence. Inspired by FIFA’s legal instruments of training compensation and solidarity mechanism for the transfer of players, we conclude by suggesting a plausible global policy to complement this authority-based approach. (shrink)

This paper aims to explore and offer different hypotheses that could account for an adequate understanding of the duty to die and its relation to biopolitics from two neglected approaches. First, death will be analysed from a biopolitical perspective to understand the crucial role it has in biopower. Second, the focus lies on the two-folded implication that death has in biopower, for it could be either a defiance of it or the final sublimation of its control. Similarly, the next section (...) addresses the relations between death and neoliberalism from a biopolitical perspective, exploring the possibility of understanding the duty to die as resistance to economic mandates or, on the contrary, as the fulfilment of neoliberal interests. Finally, as a continuation of the relations between the duty to die and neo-liberalism, the paper analyses a similar two-folded view of the former from a psychopolitical perspective. (shrink)

Las generaciones que hemos vivido los últimos años del siglo XX y los comienzos de esta nueva centuria solemos pensar que cuando este mundo sea realmente perfecto, entonces nadie tendrá que trabajar, pues es común creer que el trabajo es una de las múltiples imperfecciones de esta existencia. Ahora bien, como se sabe el hombre se encuentra arrojado al trabajo, y al ser éste un quehacer de desdicha y cansancio para él, se toman entonces dos posturas ante su “reivindicación”: la (...) primera apunta a la obtención en mayor grado de beneficios externos y riquezas y, la segunda se encamina por la trasmutación del hombre a la máquina. De manera que, la búsqueda de la retribución y la abolición del esfuerzo marcan las pautas del entendimiento sobre el trabajo en este principio del siglo XXI. La retribución es el fin del trabajo y para generar la mayor posible, no se ve como necesario el sudor de la frente. (shrink)

This paper straightforwardly addresses one of the strongest, from an ethical perspective, objections presented to the duty to die, the one concerned with the lack of a normative theory to support it, offered by Seay in his paper Can there be a “duty to die” without a normative theory? The aim of the paper is to provide strong metaethical grounds to support the duty to die without the need of a moral normative theory. First, the definition and main argument for (...) the duty to die will be presented. Second, Seay’s objection will be described and clearly explained. Third, our metaphysical assumptions and a preliminary metaethical discussion will be offered to situate and understand the context. Finally, we will show how the duty to die can be integrated within the metaethical approach previously presented, defending that there is no need of a normative theory to provide good justification and strong ethical grounds for the duty to die, because they will have already been provided by our metaethical argument. (shrink)

Euthanasia and the duty to die have both been thoroughly discussed in the field of bioethics as morally justifiable practices within medical healthcare contexts. The existence of a narrow connection between both could also be established, for people having a duty to die should be allowed to actively hasten their death by the active means offered by euthanasia. Choosing the right time to end one’s own life is a decisive factor to retain autonomy at the end of our lives. However, (...) there is no definitive consensus on why physicians should be the ones performing the medical procedure to end a person’s life. The moral problems arising from such assertion are not to be taken lightly, for medical tradition has long regarded the duty not to kill, not to actively end a patient’s life, as the core moral obligation that gives meaning to the medical profession. Our concern is to question the moral justifiability of the arguments offered by physicians not to actively help patients die. (shrink)

Se analiza la apertura del hombre a partir de su naturaleza legalizada. Ante el conflicto entre ley, physis y libertad, nos preguntamos: ¿por qué se considera la naturaleza incompatible con la libertad?, ¿por qué la legalidad parece contradecir a la apertura?, ¿ser libre significa estar lejos de cualquier atadura a la ley y a la naturaleza? El texto inicia con una exposición de las nociones de naturaleza y legalidad y de su relación con la libertad, ofrece una definición de la (...) persona basada en su comprensión yoica y su dignidad y una explicación del sentido de la apertura en la dimensión social del ser humano. (shrink)

Desde ines del siglo XX, el Desarrollo Humano (DH) ha planteado la necesidad de un cambio de paradigma que centre su atención en la mejora de la condición de vida de las personas —no únicamente desde la perspectiva de un aumento de ingreso— sino en torno al desarrollo de las capacidades fundamentales o esenciales pertenecientes al ser humano. Esta postura parte de la crítica al utilitarismo y sostiene que el DH tiene que partir de una comprensión profunda del ser humano. (...) Hasta entonces, la pregunta central del desarrollo había sido sobre la capacidad de producción de una nación. Pero, el nuevo planteamiento se preocupa por el estatus de las personas no en cuanto a la felicidad entendida como el poder de generar bienestar en función de obtener placer y evitar el dolor, sino cómo está la gente en sí misma. Entonces, el DH se reiere a un proceso y a un in en sí mismo, mediante el cual la gente accede a oportunidades para ampliar sus capacidades y funcionamientos, puesto que el sujeto de éstas es el hombre mismo. El DH como paradigma tiene que desarrollar un cuerpo teórico de carácter interdisciplinar y, en este punto, la incorporación de la ilosofía se hace urgente. Es necesario incorporar la metafísica del hombre dentro de la antropología social (AS) a la metodología de investigación del DH, a in de responder ¿Cuáles son las capacidades esenciales que le competen a los seres humanos? (shrink)

(English below) -/- Normalmente se piensa en la percepción y la memoria como dos capacidades independientes, creyendo que la primera solo tiene influencia sobre la segunda durante la codificación. En las entrevistas autobiográficas de historia oral y memoria histórica, los entrevistados seleccionan, adaptan y completan sus recuerdos para crear diferentes versiones de ellos. En este artículo se argumenta que lo anterior es consecuencia de la naturaleza simulativa de la memoria episódica, y del empleo por los entrevistados de información perceptiva para (...) generar y adaptar sus recuerdos a un discurso autobiográfico, buscando satisfacer un propósito comunicativo. Para ilustrar esto, se analizan tres factores contextuales que influyen sobre la construcción del recuerdo en una entrevista autobiográfica (objetivo comunicativo, idioma de comunicación e interacción emocional), mostrando que, en este tipo de recuperación, memoria y percepción contribuyen simultáneamente a construir simulaciones de eventos que se adaptan en tiempo real al contexto donde ocurre la evocación. /////////////Abstract/////////////// Perception and memory are usually thought to be two independent faculties, where the former is believed to only have an influence on the latter at encoding. In autobiographical interviews of oral history and historical memory, interviewees select, adapt, and complete their memories to create different versions. This paper argues that this process is a consequence of the simulative nature of episodic memory and the interviewees’ use of perceptual information to generate and adapt their memories to an autobiographical discourse with the goal of satisfying a communicative purpose. To illustrate this, three contextual factors that influence the construction of a memory in an autobiographical interview are analyzed, showing that, in this type of recall, memory and perception simultaneously contribute to constructing episodic simulations of events, which adapt in real-time to the context in which recall happens. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Many current problems surrounding science revolve around the complex epistemological framework that shapes a new vision of knowledge about reality. The traditional epistemological positions are characterized by the explanation of nature by means of concatenated facts; that is, as bricks attached to each other giving shape to the edifice of science. A conception of this nature showed that the idea of certainty was nothing more than a mere illusion, opening the way, on the contrary, to the idea of the uncertainty (...) of knowledge based on the descriptions of quantum physics, also a product of the non-reductionist conception of reality, thus criticizing the specular representation. This article addresses the main problems surrounding the critical conceptions that the emerging epistemology reveals about knowledge, pointing towards a much more complex vision of reality. (shrink)

El síndrome de Herlyn-Werner es una patología rara que afecta a las mujeres entre 0,1 a 3,8% de la población general, su etiología es desconocida pero existe una malformación congénita del útero y la vagina, el diagnóstico es tardío lo que genera consecuencias graves como la infertilidad, endometriosis secundaria, adherencias pélvicas, piosalpinx e incluso piocolpos. El tratamiento es principalmente mediante cirugía y dependiendo de la anomalía, será la intervención quirúrgica. A partir de la problemática antes descrita la presente investigación tiene (...) como objetivo desarrollar un método neutrosófico para la evaluación del Síndrome Herlyn-Werner. Es un síndrome raro que presenta complicaciones al momento de diagnosticar. Es importante la clínica y el seguimiento una vez diagnosticado. Sin embargo, la falta de estudios de este síndrome hace que no se conozca la etiología y por ende haya limitados tratamientos en estas pacientes, además de que un diagnóstico tardío aumenta la probabilidad de endometriosis e infertilidad. (shrink)

En Argentina existió una poderosa influencia de origen francés que modificó profundamente las tácticas militares y la ideología del Ejército entre 1957 y 1963. Estas teorías extranjeras importadas al Cono Sur, tuvieron como origen los aprendizajes obtenidos por el Ejército francés en las guerras de Argelia e Indochina. A partir de tales experiencias, los oficiales franceses desarrollaron técnicas de combate contra la entonces novedosa ‘guerra de guerrillas’ de los grupos rebeldes, que fueron enseñadas posteriormente a los militares argentinos. Esta enseñanza (...) incluía importantes elementos de carácter doctrinario, como la idea de la guerra global contra el comunismo, la noción de enemigo interno, y la convicción de que sus acciones, incluido el uso de tortura como técnica de obtención de información, estaban justificadas por la búsqueda del bien mayor de la nación. Esta ideología influyó profundamente en el Ejército argentino y es posible notar su rastro en el radical proceder que tuvieron los cuerpos militares durante el Proceso de Reorganización Nacional. (shrink)

El presente artículo analiza el fenómeno del mestizaje cultural que se da alrededor de la creación de la Virgen de Guadalupe. Se propone que la resignificación que se dio en torno al cerro del Tepeyac, donde originalmente se adoraba a Tonantzin, constituye un evento de creación de sentidos que se da en el contexto del mestizaje, y que incorpora la construcción discursiva de la hierofanía en torno a tres elementos: el objeto sagrado, el lugar del culto y el ritual de (...) adoración. Este evento tuvo una gran importancia, pues el guadalupanismo generó consigo una serie de sentimientos de pertenencia entre los criollos e indígenas, quienes encontraron en él una forma de entenderse como distintos al imperio español, lo que para muchos autores significó una de las primeras semillas de los ideales independentistas y la superación de la época colonial. (shrink)

El acceso a la justicia como derecho, y el diseño e implementación de políticas públicas que lo tornen operante, exige un abordaje formativo crítico que se inscriba en la línea de una triple articulación: filosófica, jurídica y política. Enmarcada en dicha pretensión, la propuesta del curso “Agencias judiciales, políticas públicas y acceso a la justicia” tiene por objeto: a)Promover la reflexión sobre el acceso a la justicia como núcleo problemático de nuestra contemporaneidad social y jurídica. b)Reinscribir dicha reflexión crítica en (...) las filiaciones iusfilosóficas que la posibilitan e impulsan. c)Conceptualizar el acceso a la justicia como desafío medular de políticas de inclusión social.d)Identificar las complejidades que se derivan del carácter críptico y técnico que reviste el derecho moderno y el lenguaje jurídico que lo constituye, circunstancia que dificulta su accesibilidad y difusión. e)Efectuar aportes formativos que sirvan de base para la elaboración de políticas de acceso a la justicia que posibiliten la desarticulación de esta opacidad y formalización del lenguaje jurídico. f)Advertir el carácter performativo que porta el derecho como práctica social discursiva no solo como esfera de producción normativa sino también de construcción de las representaciones sociales que se disputan en la escena pública. g)Comprender el rol fundamental que poseen las agencias judiciales como instancias de promoción y desarrollo de políticas públicas en materia de acceso a la justicia. h)Esbozar los desafíos de dichas agencias judiciales para la profundización del acceso a la justicia como derecho vinculado a problemáticas específicas tales como la vulnerabilidad social y la diversidad cultural y lingüística. (shrink)

El alcance de la epojé y la posterior reducción ha sido siempre uno de los mayores terrenos de disputa de la fenomenologı́a. Este ensayo tiene la pretensión de reflexionar en torno a este elemento metodológico esencial a la luz del problema del acceso al mundo. ¿Se ha perdido algo, una vez llevada a cabo la reducción? La respuesta será negativa. Para ello, en la primera sección se presentará cómo más bien hay una reapropiación originaria del mundo a través de la (...) reducción. En la segunda sección se revisará la noción de Jan Patočka de mundo como totalidad pre-dada. En efecto, ambas permiten acercarse a la conclusión de que la reducción encamina hacia un renovado acceso al mundo sin dejar nada de este fuera, permitiendo ası́ que el mundo aparezca qua fenómeno. Esto significa, finalmente, que la reducción permite reconocer de modo originario la relación de nosotros con el mundo, sin entenderla como una mera relación entre dos cosas. (shrink)

The phrase ‘person‐centred care’ (PCC) reminds us that the fundamental philosophical goal of caring for people is to uphold or promote their personhood. However, such an idea has translated into promoting individualist notions of autonomy, empowerment and personal responsibility in the context of consumerism and neoliberalism, which is problematic both conceptually and practically. From a conceptual standpoint, it ignores the fact that humans are social, historical and biographical beings, and instead assumes an essentialist or idealized concept of personhood in which (...) a person is viewed as an individual static object. From a practical standpoint, the application of such a concept of personhood can lead to neglect of a person's fundamental care needs and exacerbate the problems of social inequity, in particular for older people and people with dementia. Therefore, we argue that our understanding of PCC must instead be based on a dynamic concept of personhood that integrates the relevant social, relational, temporal and biographical dimensions. We propose that the correct concept of personhood in PCC is one in which persons are understood as socially embedded, relational and temporally extended subjects rather than merely individual, autonomous, asocial and atemporal objects. We then present a reconceptualization of the fundamental philosophical goal of PCC as promoting selfhood rather than personhood. Such a reconceptualization avoids the problems that beset the concept of personhood and its application in PCC, while also providing a philosophical foundation for the growing body of empirical literature that emphasizes the psychosocial, relational, subjective and biographical dimensions of PCC. (shrink)

How does microbiota research impact our understanding of biological individuality? We summarize the interdisciplinary summer school on "Microbiota, Symbiosis and Individuality: Conceptual and Philosophical Issues" (July 2019), which was supported by a European Research Council starting grant project "Immunity, DEvelopment, and the Microbiota" (IDEM). The summer school centered around interdisciplinary group work on four facets of microbiota research: holobionts, individuality, causation, and human health. The conceptual discussion of cutting-edge empirical research provided new insights into microbiota and highlights the value of (...) incorporating into meetings experts from other disciplines, such as philosophy and history of science. (shrink)

The Plant Ontology (PO) is a community resource consisting of standardized terms, definitions, and logical relations describing plant structures and development stages, augmented by a large database of annotations from genomic and phenomic studies. This paper describes the structure of the ontology and the design principles we used in constructing PO terms for plant development stages. It also provides details of the methodology and rationale behind our revision and expansion of the PO to cover development stages for all plants, particularly (...) the land plants (bryophytes through angiosperms). As a case study to illustrate the general approach, we examine variation in gene expression across embryo development stages in Arabidopsis and maize, demonstrating how the PO can be used to compare patterns of expression across stages and in developmentally different species. Although many genes appear to be active throughout embryo development, we identified a small set of uniquely expressed genes for each stage of embryo development and also between the two species. Evaluating the different sets of genes expressed during embryo development in Arabidopsis or maize may inform future studies of the divergent developmental pathways observed in monocotyledonous versus dicotyledonous species. The PO and its annotation databasemake plant data for any species more discoverable and accessible through common formats, thus providing support for applications in plant pathology, image analysis, and comparative development and evolution. (shrink)

The study of biodiversity spans many disciplines and includes data pertaining to species distributions and abundances, genetic sequences, trait measurements, and ecological niches, complemented by information on collection and measurement protocols. A review of the current landscape of metadata standards and ontologies in biodiversity science suggests that existing standards such as the Darwin Core terminology are inadequate for describing biodiversity data in a semantically meaningful and computationally useful way. Existing ontologies, such as the Gene Ontology and others in the Open (...) Biological and Biomedical Ontologies (OBO) Foundry library, provide a semantic structure but lack many of the necessary terms to describe biodiversity data in all its dimensions. In this paper, we describe the motivation for and ongoing development of a new Biological Collections Ontology, the Environment Ontology, and the Population and Community Ontology. These ontologies share the aim of improving data aggregation and integration across the biodiversity domain and can be used to describe physical samples and sampling processes (for example, collection, extraction, and preservation techniques), as well as biodiversity observations that involve no physical sampling. Together they encompass studies of: 1) individual organisms, including voucher specimens from ecological studies and museum specimens, 2) bulk or environmental samples (e.g., gut contents, soil, water) that include DNA, other molecules, and potentially many organisms, especially microbes, and 3) survey-based ecological observations. We discuss how these ontologies can be applied to biodiversity use cases that span genetic, organismal, and ecosystem levels of organization. We argue that if adopted as a standard and rigorously applied and enriched by the biodiversity community, these ontologies would significantly reduce barriers to data discovery, integration, and exchange among biodiversity resources and researchers. (shrink)

A coletânea apresenta, sob a forma de artigos, problemas e soluções associados ao conceito e substância ao longo da história da filosofia. Sem pretender exaurir esse percurso, a coletânea contém 29 artigos redigidos por diversos especialistas brasileiros em Filosofia. Sua proposta é oferecer uma visão clara, acessível, precisa e atualizada desse recorte da história do conceito de filosofia, na expectativa de contribuir para o aperfeiçoamento do ensino e debate de filosofia no país. -/- The anthology presents, through a series of (...) articles, the intricacies of problems and solutions intertwined with the concept of substance across the annals of philosophical history. While not seeking to comprehensively cover this vast terrain, the collection comprises 29 articles penned by a diverse array of Brazilian specialists in Philosophy. Its overarching aim is to furnish a lucid, accessible, precise, and contemporaneous perspective on this facet of philosophical inquiry, with the aspiration of enriching the landscape of philosophical education and discourse in Brazil. (shrink)

Nosotres, biólogues, ecologistas y otres profesionales dedicados a proteger la vida, les escribimos con una solicitud urgente. Les pedimos muy comedidamente que su organización o institución emita un comunicado oficial condenando la crisis en curso y abordando los impactos ambientales y humanitarios en Palestina.

Los autores presentan los resultados de un estudio con la participación de 445 estudiantes, titulado: «La adquisición del inglés por medio de las clases en línea en estudiantes de nivel superior del Complejo Regional Nororiental durante la pandemia de COVID-19»; en él, entre otras conclusiones, proponen dinamizar la práctica digital y flexibilizar los métodos de evaluación, puesto que la 25 Introducción interacción social en el aprendizaje de una lengua extranjera es imperativa para motivar a los estudiantes.

Voces de Carnaval: ritualidad festiva, resignificación cultural y mercantilismo, surge del interés de compartir experiencias de la ritualidad festiva en varias latitudes, especialmente latinoamericanas, para generar nuevos sentidos de encuentro cultural. Este espacio plural, motivado desde la Red Colombia Festiva junto con el Instituto de Estudios en Comunicación y Cultura de la Universidad Nacional de Colombia sede Bogotá, varias universidades públicas, la Universidad Politécnica Salesiana de Quito, a través de la carrera de Antropología, el grupo de investigación Filosofía de la (...) Educación GIFE y la editorial Abya-Yala, abrieron la puerta a esta polifonía de reflexiones analíticas y críticas que se decantan en este libro. El lector encontrará pensamientos diversos que re-crean la fiesta desde los cuerpos individuales y colectivos y sus formas de entender y sentir la ritualidad heredada, pero a la vez mediada por las necesidades emergentes de relacionarse y participar del goce y disfrute de la libertad como principal desinhibidor de colectivos sociales que reclaman su derecho a expresar lo que les es limitado, a través de las formas prohibidas fuera de la esfera ceremonial. (shrink)

En Diseño moviendo al Mundo se recopilan investigaciones donde el denominador de los artículos es pensar al diseño como disciplina holística que al extender lazos a otros mundos del saber aporta herramientas conceptuales y estrategias proyectuales para desenredar problemas e inspirar gráficos, objetos, servicios y sistemas para la buena vida de las personas.

Los trabajos reunidos en este libro tienen un propósito en común. Aspiran a clarificar las principales tesis de Mainländer y su relación con otros pensadores, por ejemplo, Freud, Schopenhauer, Albert Caraco, Manlio Sgalambro, Emil Cioran, Jorge Luis Borges, entre los más destacados. Enmarcado en sus aportes valiosos, este volumen es un hito cuya vasta sapiencia y rigurosidad resulta más que favorable para la recuperación y difusión de este pensador.

This paper looks at Alexander Guerrero’s epistemic case for ‘lottocracy’, or government by randomly selected citizen assemblies. It argues that Guerrero fails to show that citizen expertise is more likely to be elicited and brought to bear on democratic politics if we replace elections with random selection. However, randomly selected citizen assemblies can be valuable deliberative and participative additions to elected and appointed institutions even when citizens are not bearers of special knowledge or virtue individually or collectively.

As touch remains commonly defined by the closeness it physically implies and it rhetorically evokes, the mere notion of distant touch and of distal haptic perception seems peculiar. But Aristotle’s perspective, which I wish to take as a point of departure, is firm: we perceive the objects of touch, the hot and the cold, the hard and the soft, the curved and the sharp, through other things: δι' ἑτέρων. In this article, I would like to explore this ἕτερος by showing (...) how the otherness of perception always implies an intermediary, a middle point (μέσος), i.e. an other not so other, an other that is able to translate the much more distant otherness of the perceived object. To explore these forgotten layers of alterity that fall into what we commonly conceive of as the impalpable emptiness of distance, I propose to study the idea of distant touch from the perspective of phenomenological aesthetics. In order to do so, I will first examine some aspects of the Husserlian account of perception and will then focus on the phenomenology of distant touch in Alejandra Costamagna’s novel El Sistema del Tacto [The System of Touch] (2018). (shrink)

This paper responds to critical commentaries on my book, Perceiving Reality (OUP, 2012), by Laura Guerrero, Matthew MacKenzie, and Anand Vaidya. Guerrero focuses on the metaphysics of causation, and its role in the broader question of whether the ‘two truths’ framework of Buddhist philosophy can be reconciled with the claim that science provides the best account of our experienced world. MacKenzie pursues two related questions: (i) Is reflexive awareness (svasaṃvedana) identical with the subjective pole of a dual-aspect cognition (...) or are there alternative, perhaps better, ways of understanding this self-intimating character of mental states? (ii) Is perception constitutively intentional or is it representational? Vaidya argues that, in so far as Husserlian phenomenology and Buddhism differ in terms of their fundamental ontological commit- ments, they must be incompatible, thus rendering any cross-cultural philosophical project that seeks their rapprochement tenuous. One of my aims in Perceiving Reality is to show how accounts of perception informed by metaphysical realism can be problematic on both metaphysical and epistemological grounds, especially when relying on conceptions of consciousness that ignore its properly phenomenological features. (shrink)

Devrions-nous remplacer les élections par des loteries ? Le célèbre livre de Bernard Manin sur le gouvernement représentatif a appris à beaucoup que les Grecs considéraient les élections comme un moyen aristocratique, et non démocratique, de sélectionner des personnes pour le pouvoir et l'autorité politique, en comparaison avec le tirage au sort, où chacun a une chance égale d'être sélectionné. (Manin 1997) Jusqu'à récemment, cependant, l'idée qu'un engagement envers la démocratie nécessite de remplacer les élections par le tirage au sort (...) a suscité peu d'intérêt parmi les philosophes politiques. (Blondiaux, 2008 ; Courant et Sintomer, 2019) Cela a maintenant changé. (Abizadeh 2020) ( A. Guerrero 2014) (A. Guerrero 2021b ; 2021a) (Landemore 2020) (Owen et Smith 2018) (P.-É. Vandamme et al. 2018). Cet article pose donc la question de savoir si le tirage au sort est plus démocratique que les élections et si, pour cette raison, nous devrions l’utiliser pour compléter ou remplacer les élections ? (shrink)

Interdisciplinary dialogue acts as a symbiosis for all the areas that participate and imply enormous projections for both art and science. This paper explores the potential of an interdisciplinary dialogue between Biology and Performance using as a case study the Performance Analfabeta created by the artist Paulina Bronfman. The work was shaped in the context of The Third Conference of the Nucleus of Artistic Research (NIA) of In/Inter/Disciplinary Laboratories hosted by the Faculty of Art of The Pontificia University of Chile (...) (LAB IID). The Lab was led by Chilean biologist Alejandra Zuñiga- Feest and the Brazilian artist Adriana Parente La Selva. This work aims to explore the questions: what does it mean, from the point of view of the arts and sciences, to develop an interdisciplinary laboratory? How is this done? This paper problematizes the creative process of collaboration between sciences and performance as well as the potential impact and link with society that this multidisciplinary dialogue can have. (shrink)

The passionate and staunch defence of logic of the controversial thinker Ibn Ḥazm, Abū Muḥammad ʿAlī b. Aḥmad b. Saʿīd of Córdoba (384-456/994-1064), had lasting consequences in the Islamic world. Indeed, his book Facilitating the Understanding of the Rules of Logic and Introduction Thereto, with Common Expressions and Juristic Examples (Kitāb al-Taqrīb li-ḥadd al-manṭiq wa-l-mudkhal ilayhi bi-l-alfāẓ al-ʿāmmiyya wa-l-amthila al-fiqhiyya), composed in 1025-1029, was well known and discussed during and after his time; and it paved the way for the studies (...) of his compatriots Ibn Bājjah (d. 1138), Ibn Ṭufayl (1185), and Ibn Rushd (1198), who each gave demonstrative reasoning a privileged place within the methods of attaining knowledge. Unfortunately, as too often in the history of science, Ibn Ḥazm’s innovative perspectives and contributions in logic have been overlooked or considered with an attitude of contempt. On the one hand, his work has been seen, at best, as promulgating the benefits of studying Aristotle’s logic, so that his contribution is assessed as more didactical than conceptual. And on the other hand, those who do examine his innovations often consider them to be mistaken. As indicated by Chejne (1984, p. 2) contempt towards the logical work of Ibn Ḥazm was also present in its reception by the Eastern philosophers who accused him of deviating from Aristotelian logic and of dabbling in things beyond his capability. However, a reassessment of his work on logic has since begun, by delving into the ways the thinker of Córdoba studied the links between deontic and modal qualification of propositions. In this context Lameer’s (2013) paper on the logical sources of Ibn Ḥazm is worth mentioning; the author (p. 417, footnote 1) observes that, although, strictly speaking, it was al-Fārābī who first drew the parallelism between deontic and modal concepts, it was Ibn Ḥazm who developed it and worked it out in a more precise manner. A primary aim of this paper is to help fill some of these gaps by stressing the role of the work of Ibn Ḥazm in developing a notion of deontic necessity deeply rooted in legal normativity, and in explicitly discussing the transference between deontic and modal concepts. According to our view; the basic units of Islamic deontic logic are what we might call, indulging in terminological anachronism, heteronomous imperatives. As it turns out, the heteronomy of imperatives within Islamic legal systems contrasts with those of the purely moral realm, which seem to be closer to an autonomous conception of moral law. There it concurs again with Leibniz’s proposal to define obligatory as “what is necessary for a good person to do”. In the present paper, we will focus on the heteronomous imperatives of legal systems rather than on the imperatives of the purely moral realm. In this context, the work of Ibn Ḥazm extends the parallelism between the necessity of events and that of human actions stressed by his predecessors. According to our understanding, Ibn Ḥazm’s parallelism can be rendered explicit formally by means of a conditional (or hypothetical) structure shared by both deontic and modal propositions. Moreover, this structure makes apparent that this parallelism displays an underlying system of “degrees”. Indeed, while in the domain of events, given some conditions, it makes sense to distinguish between an event that is more likely to happen than another. Ibn Ḥazm speaks of near and distant possibility (such as the higher degree of likelihood of rain, given the condensation of clouds in December, and its lower degree, when the condensation occurs in summer); and, in the domain of actions, the Islamic notion of weighting actions determines degrees of virtue (or of legal and moral value). So whereas the degree of virtue of performing a forbidden act as determined by the distribution of sanction and reward is 0, we obtain the same value by pondering the likelihood of an impossible event to take place. Furthermore, as discussed in section II.3.2, the system of values at work in the parallelism can be seen as opening the way to a more direct correspondence. Thus, while in the realm of nature, likelihood of occurrence of an event is dependent upon the conditions specific to the occurrence of that event; while, in the realm of jurisprudence, likelihood of performing an action is dependent upon the distribution of reward and sanction specific to that action (being that, given the choice to perform or not perform a given action, those that will be rewarded are more likely to be performed than those that are not). According to this perspective, the point of the parallelism is that both deontic and modal qualifications measure the degree of an action or event to become actual; that is – indulging once more in anachronism (but this time from the Leibnizian background) – the degree measures how feasible (facile) an action or event may be. This suggests that Ibn Ḥazm’s perspectives already herald the links to probability and possibility explored by Leibniz six centuries later – see for example Leibniz’s (1671, A VI, I, p. 424-26) use of probability in the context of conditional right. Nevertheless, it also shows a crucial difference to the approach developed in the Elementa Jura Naturalis: whereas Leibniz’s studies seek to define what is to be just or virtuous, the logical system of deontic imperatives within Islamic jurisprudence presupposes that what is to be virtuous has already been settled. Determining what is to be virtuous is not achieved by logical reasoning within the system of legal jurisprudence, but by delving into the higher objectives of the Sharīʿa. While developing our point, we will delve into the logical structure of the heteronomous imperatives. This distinguishes our contribution from the existing literature, such as the papers of Chejne (1984), Lameer (2014), and Guerrero (1997, 2010, 2014), which do not provide a logical analysis of the deontic concepts put into work by Ibn Ḥazm. The true antecedent to the present paper is the work of Farid Zidani (2007, 2015), who, so far as we know, was the first to undertake such a task. Some of our own developments and general epistemological thoughts go beyond Ibn Ḥazm’s framework and motivations; mainly those contained in sections II.3.2 and IV. However, according to our view, these reflections suggest that Ibn Ḥazm’s approach has the substance for a broader and deeper exploration of the logic of norms. The paper is structured as follows:I.Ibn Ḥazm’s Logic of Heteronomous Imperatives. After presenting some extracts of the relevant text, we proceed by providing a formal reconstruction of the five forms of deontic modalities. II. A Landmark in the History of the Logical Analysis of Norms. Duties and Modalities. In this section, we study the transferences from deontic to modal necessity and possibility. We briefly compare the deontic system of Islamic Jurisprudence with that of Leibniz.III. Leibniz and Hypothetical Imperatives in Law.IV. Beyond Ibn Ḥazm: Conclusions and the Work Ahead. We will conclude the paper by discussing briefly some conceptual points that distinguish the logic of heteronomous imperatives from contemporary deontic logic. Our final words will discuss deontic-modal parallelism in the context of Ibn Ḥazm’s rejection of reasoning by conjecture and what we call “the internalization of nature.”. (shrink)